VIVALDI project is developing an innovative, sustainable, and cost-efficient biotechnological solution to convert off-gas emissions from bio-based industries into 4 organic acids: lactic acid (LA), succinic acid (SA), itaconic acid (IA) and 3-hydroxypropionic. In this way, the industry’s greenhouse gases emissions will not only be reduced but will be used as a novel feedstock, lowering the dependency on fossil fuels import and the exploitation of key resources such as energy, raw material, freshwater, and land.